The Department of Human Health and Nutritional Sciences at the University of Guelph is seeking research participants 50-85 years of age with Parkinson’s disease to complete a 10 week exercise training study in collaboration with the Guelph YMCA. This study is funded by a 2018 Parkinson Canada Pilot Project Grant.

We are interested in comparing the ability of two different cycling programs on improving your balance, strength, mobility, and cardiorespiratory health.

To be included you must not have a history of dementia, stroke, diabetes, autonomic neuropathy, or recent smoking (< 6 months). You must be able to stand unsupported for 1 min, walk 18 m without use of an aid, and mount a stationary bike.

You would be asked to attend 2 pre-training and 2 post-training visits (~6.5 hrs) at the University of Guelph campus and complete 10 weeks of exercise training (3x/week; total ~30 hrs) at the Guelph YMCA.

We can discuss reimbursement for your transportation costs to the University. There is a small financial compensation available for this study.

If you are interested in participating or would like more information, please contact either:

Lori Ann Vallis, PhD (lvallis@uoguelph.ca) call (519) 824-4120 ext 54589


Philip Millar, PhD (pmillar@uoguelph.ca) call (519) 824-4120 ext 54818




Ambroxol as a novel disease modifying treatment for Parkinson’s disease dementia: a single-centre, randomized, double-blind, placebo-controlled trial

 Why is this study needed?

  • Current medications for the treatment of cognitive decline in Parkinson’s disease are helpful, but do not change the course of disease progression.
  • Cognitive decline is one of the main contributors to decreased quality of life , as well as increased risk of institutionalization and mortality among individuals with Parkinson’s disease.
  • The development of therapies that could delay memory loss in Parkinson’s disease is critical.

What is a clinical trial?

Clinical trial is a scientific investigation of a new therapy, such as new medication. Common questions addressed in clinical trials include:

  • Is the medication safe and well- tolerated?
  • Is the medication effective?
  • What is the best dose?

Participation in clinical trials contributes to the development of new treatments for debilitating medical conditions such as Parkinson’s disease.

 What is the Ambroxol Clinical Trial for Parkinson’s disease Dementia (PDD)?

The aim of this trial is to investigate the safety and tolerability of Ambroxol in individuals with PDD.

· Ambroxol is a cough medicine that has been available over the counter in more than 50 countries for over 30 years, but is not available in Canada or the USA.

· Ambroxol has an excellent safety record

· Ambroxol is thought to reduce the levels of a protein in the brain (i.e. alpha-synuclein) that is linked to the progression of Parkinson’s disease

What taking part in the Ambroxol clinical trial involve?

  • If you decide to participate in this research, you will be invited for a screening visit, when the research team will assess your eligibility for the study
  • If you are eligible for the study, you will be randomized into one of two groups: Ambroxol (1050mg) or placebo.
  • The study will last 1 year and involve 11 visits to Parkwood Institute (London, ON)
  • In these visits we will collect blood and urine samples to ensure safety. The study doctor will also exam you.
  • At the beginning (month 0), middle (month 6), and end (month 12) the research team will assess your memory, thinking, movements, daily functioning and behaviour.
  • An MRI will be done at the start and end of the study.

Can I participate in the Ambroxol clinical trial?

You may be eligible for the Ambroxol study if you:

  • 50 years old or older
  • If your Parkinson’s disease diagnosis preceded changes in memory and thinking by at least 1 year
  • If you have a caregiver who sees you at least 4 times a week and is willing to be your study partner
  • If you are taking appropriate medication for you Parkinson’s disease symptoms

Who can I contact about the study?

For more information about the Ambroxol clinical trial for Parkinson’s disease dementia contact the study coordinator:

Carolina Silveira

Phone: 519-646-6100 ext. 42367

Fax: 519-646-6226


End Date: 






Getting Older Adults Outdoors (GO-OUT) Study

Are you an older adult who wants to improve your ability to walk outdoors?

What is the GO-OUT study? We are a group of students, physical therapists and researchers from universities in Montreal, Toronto, Winnipeg & Edmonton. We wish to evaluate two programs to help seniors to walk outside more easily.

Who are we looking for? We are looking for adults aged 65 years and older who are interested in walking outside for exercise during the summer.

What will you have to do? You will participate in four evaluations spread out over one year. After the first evaluation, we will use a process that is like flipping a coin to assign you to one of two programs. The programs are:

GO-OUT Workshop & Coaching Program: This program involves a workshop and weekly coaching. Participants will attend an interactive workshop to learn strategies and skills to walk safely outdoors. You will move between stations at which you will practice using a step counter and Nordic walking poles; learn about fall prevention, and footwear, and perform balance exercises. Lunch will be provided. After the workshop, a coach will call you weekly for 10 weeks to coach you to walk outdoors.

GO-OUT Workshop & Outdoor Walking Program: This program involves the same workshop as described above, but you will also participate in an outdoor walking group, led by a physiotherapist, for 10 weeks. In the outdoor walking program, you will meet as a group in a nearby park, twice a week, for 10 weeks.

When and where will the programs run? The GO-OUT workshop will take place in June 2019. The weekly coaching and outdoor walking group will run from June to August, 2019. These dates are tentative.  Please see below to get more information for your city.

Is there a cost to participate? No. The GO-OUT programs are FREE of charge as funding is provided through a grant. All participants will receive a free step counter and workshop workbook.

If you are interested in participating, please click below for details and contact information for your city:

Montreal – Project coordinator, email: outcomesrus@mcgill.ca, phone: (514) 934-1934 (ext 36902)

Toronto – Kyla Alsbury, email: GOOUTstudy@utoronto.ca, phone: (416) 946-7579

Winnipeg – Caryne Torkia, email: go.out@umanitoba.ca, phone: (204) 787-8015

Edmonton – Dr. Allyson Jones, email: GOOUT@ualberta.ca, phone: (780) 492-1610



End Date:  June 2020.


Êtes-vous atteints de sclérose en plaques ou de la maladie de Parkinson?

Nouse recrutons présentement des homes et des femmes atteints de la maladie de Parkinson ou de la sclérose en plaques pur un projet de recherché sur l’impact des symptoms de ces maladies.

Si vous acceptez de participer, vous devrez seulement répondre à un questionnaire en ligne.

Cette etude aidera à sensibiliser les médecins face aux symptoms associés à la sclérose en plaques et à la maladie de Parkinson.

Les patients qui désirent participer peuvent consulter notre site web à l’addresse suivante:



Do you have multiple sclerosis or Parkinson’s disease?

We are recruiting women and men with Parkinson’s disease or Multiple Sclerosis for a novel research projet looking at the burden of symptoms in these diseases.

The study:

  • Only necessitates filling in an online questionnaire (5 minutes)
  • Will help raise awareness of physicians to symptoms accompanying Multiple Sclerosis and Parkinson’s disease.

Patients willing to participate are invited to visit our website at:


End Date:  Open





July 2018

Research Participants Needed for Brain Imaging/Stimulation Study                                                                                                                                                                                                                                                                              

We are seeking subjects with Parkinson’s Disease to participate in our research study that involve brain imaging/stimulation to assess the effect tDCS and understand its underlying mechanism on cognitive dysfunction


Magnetic Resonance Imaging (MRI)

Transcranial Direct Current Stimulation (tDCS)

Motor & Neuropsychological exams



Deer Lodge Center/ Movement Disorder Clinic-  2109 Portage Ave, Winnipeg, MB R3J 0L3

Kleysen Institute for Advanced Medicine at HSC-  710 William Ave, Winnipeg, MB R3E OZ3



Principle investigator: Dr. Ji Hyun Ko

Coordinator: Ms. Kelly Williams

Phone: 204-940-8427

Email: kwilliams3@mdc-dlc.ca


* If you don’t have Parkinson’s disease, and you would like to participate in our other brain imaging research trials, please contact our research coordinator (Dr. Abrar Alhindi, alhindia@myumanitoba.ca)







July 2018

Rhythmic Speech Cueing as a Clinical Tool to Improve Hypokinetic Dysarthria in Individuals with PD                                         

We are looking for people to participate in an experiment that studies how Parkinson’s Disease affects articulatory coordination in speech.

We target two groups of speakers to participate

1) Canadian-English speakers (age 18+) diagnosed with Hypokinetic Dysarthria due to Parkinson’s Disease.

2) Canadian-English speakers (age 18+) without Parkinson’s disease or any other neurogenic disorder


The goal of this study is to answer the question how (speech-) rhythm affects how people with Parkinson’s Disease move and coordinate their articulators, i.e., tongue, lips and jaw, required for linguistically correct productions. In addition, an important part of the proposed study will investigate how synchronizing with an external auditory cue affects speech production of individuals with and without Parkinson’s disease.

The experiment:

If you agree to participate in the study, you will be asked to produce a variety of speech tasks while your speech movements will be recorded using a state-of-the-art computerized movement tracking system (EMA). The session lasts approximately 2 hours in total. If you are interested, please contact us sending a personal message, or by email to set up an appointment.

We are looking forward to hearing from you.


Dr. Anneke Slis

Phone: 416-9468552

Email: odlspeech@gmail.com

Dr. Corene Thaut

Phone: 416-700-1525

Email: Corene.Thaut@utoronto.ca



May 2018




Researchers at McGill University and the Montreal Neurological Institute are seeking adults with Parkinson’s disease for a walking and brain imaging study.

The study requires 3, two-hour visits to the lab located at the Currie Athletics Centre (475 Ave des Pins). Parking or transport within Montreal is available. Testing will require walking on a specialized treadmill and brain imaging. PET images of the brain will be taken that requires an injection. Compensation for time and effort will be provided ($100).

Participant Requirements:

-Adult with Parkinson’s disease.

-Able to walk independently (without the use of a walking aid) for 40 minutes.

-Comfortable with MRI and PET imaging of their brain (non claustrophobic)

If you are interested in participating, or would like more information, please contact:

Dorelle Hinton, MSc


514-398-4184 ext 09833


May 2018


You are invited to participate in a Focus Group Study titled “Parkinson Disease Care Partnerships:  Bridging Perspectives in Clinical Self-Management Interventions”

We are recruiting for 3 focus groups involving:

  1. People diagnosed with Parkinson’s disease (PD);
  2. Primary care partners/informal caregivers of those diagnosed with PD; and
  3. Healthcare professionals caring for those living with PD to participate in a research study investigating how self-management skills are taught in clinical settings and how healthcare professionals can meet the needs of care partnerships living with PD. The study will involve one focus group at a local community centre with 3-5 other participants of the same category. You will be asked questions about how important self-management skills are to you and how healthcare professionals meet these needs. The focus group will last 30-60 minutes.

In order to be eligible for this study, you must:

  1. Be one of the following:
    1. An individual diagnosed with Parkinson disease by a neurologist, OR
    2. The primary care partner for a person diagnosed with PD for at least one year, OR
    3. A healthcare professional who treats at least 6 people with PD per year (e.g., neurologist, physiotherapist, occupational therapist, nurse, etc.)
  2. Be able to communicate in English about your experiences associated with Parkinson disease. You must be able to recall and describe past experiences.
  3. Not have a neurological condition other than PD.

Please call/e-mail Danielle Hudson for more information if interested! Phone: 519-870-0672

E-mail: dbellbou@uwo.ca

Principal Investigator: Dr. Denise Connelly


519-661-2111 ext 82238



UofT logo

February 2018

 You are invited to participate in a study entitled “Family Perspectives on Assisted Dying.”

Who we are:
We are a team of four researchers from the University of Toronto – two are student occupational therapists and two are professors at the university.

Why we are doing this:
Assisted dying is now an option for individuals eligible in Canada. The change in the law is intended to offer more options, but it may also make some people feel more concerned. There are checks and balances in place to try to prevent any improper use of assisted dying and to promote informed decisions made by the individual who is considering assisted dying.

While some researchers have examined family members’ support of assisted dying, we know very little about the attitudes and perspectives of family members regarding this issue and no research has been conducted to date in Canada. The purpose of this study is to gain further insight into the attitudes, perspectives and experiences of family members now that assisted dying is a legal option.

The findings of this study will contribute to recommendations for supporting both patients and their family members during the dying process.

Who we are asking:
We are asking family members (including close personal friends) who are or who have been involved in the care of individuals with a grievous and irremediable condition to participate in this study. The care recipient must be or have been eligible for health services in Canada. The care recipient does not or did not need to be eligible for assisted dying under the current law in Canada.

What we are asking:
This study asks for your thoughts on the how the legalization of assisted dying affects:
1) Your role in the care of someone who may or may not be considering a legal request for assisted dying;
2) The impact of this role on your health and well-being;
3) Your potential needs for support from the healthcare and social systems.

We will also be asking some general information about you (for example, age and education), but we will not be asking for information that can identify you.

How we’re asking:
We will be asking you to complete a telephone interview for this study by May 2018. We will need to arrange to contact you for the interview, but will delete your contact details once it is complete. We will record the interview anonymously- without any identifying details- so that we can transcribe it. We will ask you at the end of the interview if you still feel or wish your responses to be included – you can then ask to have it deleted if you wish for any reason.

The interview recording will be kept for transcription and then deleted. As we will not have any way to identify each recording, or the transcripts, there will be no way to delete it once it is added to the other responses. Any potentially identifying details will be de-identified or removed.

You also have the option to complete an online survey in place of the telephone interview. We are using a survey system called Survey Monkey. The survey asks for no identifying information from you – only some general demographics. We ask that you take care not to include any identifying details in the open comments sections. If any identifying details are included, we will omit them from any reports/publications/ presentations about this study.

The survey will be open until the end of May 2018. If you wish to withdraw from the survey once you have started it, you can simply click ‘discard’ at any time – this will remove any responses you have entered. Once you click ‘submit’, your responses cannot be removed.

To go to the survey, you can click on the web link below. The first page of the survey will repeat this letter – you can skip it and go to the second page where you will find the consent page.


Please feel free to forward this invitation to any others who are or have been in a position similar to you.

If you have any questions about the survey, please do not hesitate to ask either of the MSc student researchers:

Simon McKendry (s.mckendry@mail.utoronto.ca) or Kyle DIab (k.diab@mail.utoronto.ca);

or the professors:

Kevin Reel (kevin.reel@utoronto.ca) or Jill Cameron (jill.cameron@utoronto.ca).

This project has been approved by the University of Toronto Health Sciences Research Ethics Board. If you have any questions about your rights as a participant you may contact them via the Office of Research Ethics: ethics.review@utoronto.ca  or  416-946-3273.

Thanks for considering participating in this survey.

  • Simon McKendry, MSc (OT) candidate,
    University of Toronto
  • Kyle Diab, MSc (OT) candidate,
    University of Toronto
  • Kevin Reel, OT Reg. (Ont.)
    Assistant Professor (status only), Occupational Science and Occupational Therapy
    Faculty, Global Institute for Psychosocial, Palliative and End-of-life Care
    Member, Joint Centre for Bioethics
    University of Toronto
  • Jill Cameron, PhD
    Associate Professor, Occupational Science and Occupational Therapy
    University of Toronto


Caregiver Resilience and Coping Resources

Participants Needed

For a study examining the influence of self-efficacy and language on caregivers’ resilience and the association between caregivers’ attitude towards social supports and resilience.

Download a PDF Flyer here for more details about the study.

Participant Requirements

  • Informal caregivers for a person requiring assistance with one or more activities of daily living.
  • Caregivers must be older than 18 years of age.
  • Monolingual and bilingual caregivers.
  • Residing in North American continent.
  • Complete questionnaire through one of three methods: online, mail-in form or through in-person interview.
Participants have a chance to win one of five $10 Tim Horton’s gift cards.

Download the mail-in form.

For more information or to participate in this study, contact:
Joanna at joanche8@my.yorku.ca or Tonino at tonino8@my.yorku.ca


Predict Parkinson’s studies

The Nova Scotia Health Authority, Dalhousie University and IWK Health Centre, are seeking two sets of participants to investigate better ways of detecting Parkinson’s disease.

Participants will take a smell identification test (scratch and sniff), which can be mailed to your home. Some participants will have the option to have a brain MRI. If you are chosen to have an MRI, compensation for your time will be provided.

Requirements include:

  • You are between the ages of 40 and 65.
  • You are in good physical health.
  • For one set of participants: You DO have a first degree relative (parent, sibling or child) who has been diagnosed with Parkinson’s disease.
  • For a second set of participants: You DO NOT have a first degree relative (parent, sibling or child) who has been diagnosed with Parkinson’s disease.

More information for participant with a first-degree relative with Parkinson’s.

More information for participant with a first-degree relative without Parkinson’s.

If you are interested in participating, or would like more information, contact: pdadstudy@gmail.com or call 902-473-3147. Please provide your name, phone number and the best time for us to reach you.


Fall risk factors in Parkinson’s disease

Physical therapy researchers from the College of Rehabilitation Sciences at the University of Manitoba are conducting a study to evaluate fall risk factors in individuals with Parkinson’s disease (PD).

The study will evaluate participants’ ability to balance and walk while performing various mental tasks (i.e. dual-tasking.) For example walking while avoiding obstacles or while searching and tracking moving visual targets.

Click here for one-page summary.

Requirements include:

  • Individuals with Parkinson’s disease, between the ages of 55- 70.
  • Can walk independently at least 50 meters with, or without, a cane.
  • Without any musculoskeletal impairment or uncontrolled cardio-vascular condition which prevent you from walking on a treadmill for periods of 2-4 minutes.
  • Without any visual impairment that would limit your ability to watch and follow various visual images on a TV or computer monitor.

If you are interested in participating, please contact:

Mayank Bhatt

Dr. Tony Szturm


Evaluation of Parkinson’s disease questionnaire used by speech pathologists

The University of Sydney in Australia is conducting an online survey of Registered Occupational Therapists to examine the perceived knowledge, attitudes, behaviours, and barriers of occupational therapists regarding the use of psychological strategies in their practice with clients living with Parkinson’s disease.

This study involves the evaluation of a disease-specific questionnaire that assesses the physical and social effects of PD on speech, swallowing, communication. Determining the appropriateness and accuracy of this questionnaire will help health professionals to better understand the needs of persons with PD in order to provide appropriate care and support.

All potential participants will be invited to go to the questionnaire’s website. Upon opening the website, the participant will be asked to read a Participation Information Statement and to provide consent to proceed with the questionnaire. The questionnaire will take approximately 25 to 30 minutes to complete. The information gathered will be used to evaluate the appropriateness and accuracy of the questionnaire.

If the participant leaves their email address, we will contact them after 2 weeks and will ask them to complete a shorter questionnaire with fewer questions. This will take them approximately 10 minutes to complete.

While the study is primarily being conducted in Australia, the validation of the questionnaire is for a general English-speaking population. The study’s aim is on improving healthcare services and providing better resources for assessing Speech and communication symptom severity in Parkinson’s patients in Australia, but we hope to generalize this improvement for patients across English-speaking countries.

Click here for a 3-page summary of the study (PDF)

Requirements include:

  • Aged 18 years or over
  • Diagnosis of Parkinson’s Disease
  • English-speaking
  • Ability to complete the questionnaire

Participants are asked to complete an online, 30-minute or less, survey here.


Toronto Western Hospital looking into the build-up of iron in the brains of people with Parkinson’s

Researchers at Toronto Western Hospital are looking for participants for the SKY study (Study of Parkinson’s Early Stage). They are taking a new approach to treating Parkinson’s disease by looking at the build-up of iron in certain regions of the brain among people with Parkinson’s disease. It is not known whether this build-up of iron is causing harm to the brain cells, or whether removing it may improve the motor symptoms of this disease or slow its progress. The SKY clinical study aims to address these questions.

Click here for a one-page summary of the study (PDF)

Requirements include:

  • Male or female aged 18 to 80 years
  • Body weight more than 60 kg, but less than 100 kg.
  • Parkinson’s disease newly diagnosed in the past three years.
  • Currently taking antiparkinsonian medication

If you are interested, please call: 416-603-5800 x5234


Biomedical technology for individuals with Parkinson’s disease

Researchers at Simon Fraser University are inviting people with Parkinson’s disease to participate in a research study to examine the effect of Galvanic Vestibular Stimulation (GVS) on gait.GVS is a process of sending specific electric messages to a nerve in the ear, by placing non-invasive electrodes behind the ear.Electroencephalography (EEG), Electromyography (EMG), accelerometry, and simulated walking environment system will be used for data collection.

Click here for one-page summary of the study.

Requirements include:

  • Resident of Metro Vancouver area
  • Age between 35-85 years
  • Diagnosed with Parkinson’s disease or Parkinsonism

Study will run for approximately 2 hours and participant will receive $25 for time compensation.

If you are interested, please contact:

Eunice Kuatsjah
(778) 385-6810

Bindu Mohan


Understanding the neural correlates of steering of gait in Parkinson’s disease with freezing of gait

Researchers in the dept. of Kinesiology at McGill University are conducting a study to determine the effects of Parkinson’s disease with, and without, freezing of gait on the activation of the brain regions involved in turning and changing direction while walking.

Participants would need to make three, two-hour visits to the lab located beside the Montreal Neurological Institute at McGill University (downtown campus) at 475 Avenue Des Pins (parking available.) You will be asked to complete two different walking exercises in combination with brain imaging.

Requirements include:

  • Person with Parkinson’s disease
  • Able to walk independently (without use of walking aid) for 40 minutes.

If you are interested in participating, or would like more information, contact Trina Mitchell at trina.mitchell@mail.mcgill.ca or call 514-398-4184, ext. 09833.


Examining the Prevalence and Associations of Health and Mobility in Canadians

Here is a chance to participate in a study funded by the University of Waterloo International Research and Partnership Grant to examine the effects of health on mobility among Canadians.  The aim is to determine how health as well as physical, cognitive and social factors influence injury rates including driving and fall related accidents. Findings from this project will lead to program and service development that address the needs of Canadians as they age. Follow up studies will be done in 5 year intervals to see how health, mobility, driving practices, the environment, activity levels and cognitive function have changed.  Comparing data every 5 years will result in greater understanding of health and mobility trends among an aging population. For additional insight findings from this study will be compared to residents of France, who have completed the same survey.

Requirements include:

  • Over 45 years of age
  • Complete a 90 question online survey about your health, attitudes and behaviours, mobility, social demographic factors, driving, falls and a few questions on memory, sleepiness and distraction

To complete the survey in English, please click on:

Pour l’enquête en Français, vous pouvez suivre le lien ci-dessous: https://fr.surveymonkey.com/r/canadien_sante_mobilite_enquete_fr

Facebook Page:

For any questions you may contact Sarah Laberge at 519-878-1637, email selaberg@uwaterloo.ca, or the Principal Investigator Dr. Alexander Crizzle at 306-966-2773, email alex.crizzle@usask.ca.